Multidrug and toxin extrusion

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August undefined, 2024

Web4 ian. 2024 · The multidrug and toxin extrusion (MATE) transporter family comprises 70 members in the Medicago truncatula genome, and they play seemingly important, … WebI was trying to find out what factors affect the elimination of methamphetamine metabolites from the body, and found this article: Interaction and Transport of Methamphetamine and its Primary Metabolites by Organic Cation and Multidrug and Toxin Extrusion Transporters

MULTIDRUG AND TOXIN EXTRUSION PROTEINS Request PDF

Web11 iul. 2024 · A transport assay of BBR using rat Madin–Darby canine kidney (MDCK)-multidrug and toxin extrusion protein 1 (rMate1) cells and a transcellular transport assay using MDCK-multidrug resistance protein 1 (MDR1) cells were conducted to evaluate the efflux mechanism. Tissue distribution and excretion of BBR were measured using liquid ... Web1 aug. 2016 · Multidrug and toxin extrusion transporters (MATEs) have a determining influence on the pharmacokinetic profiles of many drugs and are involved in several clinical drug-drug interactions (DDIs). hot or rot

Discovery of potent, selective multidrug and toxin extrusion ...

WebAcum 1 zi · multidrug and toxin extrusion protein. MCP-1: monocyte chemoattractant protein. MDR: multidrug resistance protein. MMP: matrix metalloproteinase. MRP: multidrug resistance-associated protein. NF-κB: nuclear factor kappa B. NLRP3: nucleotide-binding domain, leucine-rich–containing family, pyrin domain–containing-3. WebhMATE1 (human multidrug and toxin compound extrusion-1; encoded by SLC47A1) is thought to have an important function in the renal and hepatic elimination of drugs, endogenous compounds and environmental toxins. The goals of this study were to identify genetic variants of hMATE1 and to determine their effects on hMATE1 transport function. WebMATE (multidrug and toxic compound extrusion) transporters play multiple roles in plants including detoxification, secondary metabolite transport, aluminium (Al) tolerance, and … lindsey house

84-5064-96 SLC47A2 (Multidrug and Toxin Extrusion Protein 2, …

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WebAmong the SLC47 family, multidrug and toxin extrusion protein 1, or MATE1 (SLC47A1 ), an organic cation/proton exchanger, mostly expressed in hepatocytes and renal tubular … Web(ABC) transporter family, multidrug and toxin extrusion (MATE) family, small multidrug resis-tance (SMR) family, and major facilitator super-family (MFS) (Spengler et al. 2024; … lindsey housing managerWeb4 oct. 2016 · Introduction. hMATE1 (human multidrug and toxin compound extrusion-1), encoded by SLC47A1, is a newly identified organic cation/H + exchanger expressed in the apical membrane of renal tubule cells and the canalicular membrane of hepatocytes. 1 hMATE1 has been shown to mediate the cellular uptake of structurally diverse small … lindsey house tulsa

"WebHuman multidrug and toxin extrusion 1 (MATE1/SLC47A1) transporter: functional characterization, interaction with OCT2 (SLC22A2), and single nucleotide polymorphisms … " - Multidrug and toxin extrusion

Multidrug and toxin extrusion

Structural biology of the multidrug and toxic compound extrusion ...

Web27 ian. 2024 · Members of multidrug and toxin extrusion (MATE) transporters are imparted in the secondary metabolites transportation. In this study, we identified 53 MATE family members in the diploid Fragaria vesca genome. Based on homologous strategies, we obtained a potential AtTT12 orthologue in the octoploid strawberry, nominated as … Web29 aug. 2014 · The multidrug and toxin extrusion (MATE) family of transporters plays a central role in clearing the body of cationic, xenobiotic compounds. Expressed principally in the kidney and liver, they...

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Web27 apr. 2024 · Here we investigated the potential role of multidrug and toxin extrusion protein 1 (MATE1) for translocation of TMAO across the luminal membrane of proximal tubular cells. HEK293 cells stably... WebExpression of a Shiga-Like Toxin during Plastic Colonization by Two Multidrug-Resistant Bacteria, Aeromonas hydrophila RIT668 and Citrobacter freundii RIT669, Isolated from Endangered Turtles (Clemmys guttata).

Web6 aug. 2024 · The multidrug and toxin extrusion (MATE) transporters catalyze active efflux of a broad range of chemically- and structurally-diverse compounds including antimicrobials and chemotherapeutics, thus contributing to multidrug resistance in pathogenic bacteria and cancers. Multiple methodological approaches have been taken … Web29 aug. 2014 · The multidrug and toxin extrusion (MATE) family of transporters plays a central role in clearing the body of cationic, xenobiotic compounds. Expressed principally …

Multi-antimicrobial extrusion protein (MATE) also known as multidrug and toxin extrusion or multidrug and toxic compound extrusion is a family of proteins which function as drug/sodium or proton antiporters. Vedeți mai multe The MATE proteins in bacteria, archaea and eukaryotes function as fundamental transporters of metabolic and xenobiotic organic cations. Vedeți mai multe The multidrug efflux transporter NorM from V. parahaemolyticus which mediates resistance to multiple antimicrobial agents (norfloxacin, kanamycin, ethidium bromide etc.) and its … Vedeți mai multe These proteins are predicted to have 12 alpha-helical transmembrane regions, some of the animal proteins may have an additional Vedeți mai multe The following human genes encode MATE proteins: • SLC47A1 • SLC47A2 Vedeți mai multe • Solute carrier family • Resistance-Nodulation-Cell Division Superfamily (RND) Vedeți mai multe Web13 sept. 2012 · Multidrug And Toxin Extrusion (MATE; SLC47A) proteins are efflux transporters mediating the excretion of several antimicrobial drugs as well as other …

Web9 ian. 2009 · H + /organic cation antiporters (multidrug and toxin extrusion: MATE1 and MATE2-K) play important roles in the renal tubular secretion of cationic drugs. We have recently identified a regulatory...

WebMultidrug and toxic compound extrusion (MATE)-type transporters, which were first identified as a bacterial drug transporter family, are present in almost all prokaryotes and … hot or schrottWebMATE2 (multidrug and toxin extrusion 2) Aliases: MATE2-B, MATE2-K, MATE2K Gene name: Solute carrier family 47 member 2 (SLC47A2) Summary MATE2 and its splice variant MATE2-K are proton antiporters which function as a poly-specific efflux transporters of diverse substrates, primarily of organic cations. lindsey housing softwareWebアズワンの【AXEL】84-5064-96 SLC47A2 (Multidrug and Toxin Extrusion Protein 2, Solute Carrier Family 47, Member 2) 100ul 492136のコーナーです。AXELは研究開発、医療介護、生産現場、食品衛生など幅広い分野に750万点以上の品揃えでお応えする商品サイト。3000円以上ご注文で送料無料。 hotor shammy towelWeb(ABC) transporter family, multidrug and toxin extrusion (MATE) family, small multidrug resis-tance (SMR) family, and major facilitator super-family (MFS) (Spengler et al. 2024; Coyne et al. 2011). Efﬂux pumps are known to consist of several transporters, which can be categorized according to high speciﬁcity with substrates, phy- lindsey howell filmsWeb30 iun. 2024 · On the apical membrane of proximal tubular cells, there are efflux transporters, such as multidrug and toxin extrusion proteins. The secretion process across the apical membrane into the lumen occurs via efflux transporters which plays an important role in serum creatinine (sCr) elimination in urine. lindsey howard attorneyWeb6 apr. 2024 · Multidrug and toxin extrusion (MATE) is a H⁺/organic cation antiporter that is highly expressed in the brush border membrane of PTCs and mediates the efflux of organic cations, including ... lindsey howard jackson kyWeb5 apr. 2024 · Multidrug and toxic compound extrusion (MATE) proteins are responsible for the efflux of cationic chemicals across cell membranes. In humans, there are two … lindseyhouse.org